Medication

• Pain and poor sleep might  respond to low-dose tricyclic ‘antidepressants’. (Their rationale should be explained.)
• Anxiety and depression might respond to the less sedating antidepressants in full doses.
• Antidepressants have not been shown to be effective, but are widely used in the management of CFS in the absence of mood disorder.
• Consider analgesics for headache or muscle pain.
• Severe or neuropathic pain might require management by a specialist pain service or neurologist.
• Be aware that some patients are sensitive to a wide variety of drugs, and doses may need to be reduced accordingly.
  

Last edited: 15/9/2003

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